Toxicology SIG

Objectives

To provide a forum to discuss the statistical issues involved in Regulatory and Investigative Toxicology.

Who we are

Our membership consists of statisticians at CROs, pharmaceutical companies and academia who are working in pre-clinical areas such as:

- Acute Tox
- General Tox
- Toxicokinetics
- DMPK
- ECG
- Repro Tox
- Genetic Tox
- Immuno Tox
- Toxicogenomics
- Histopathology
- Safety Pharmacology
- Carcinogenicity

We discuss diverse topics ranging from Dog Telemetry data analysis to Decision Trees, from Bayesian methods to dealing with irate study directors, and now have a list of over 50 affiliates on our e-mail distribution list.

How to get in touch

Join our mailing list by e-mailing this address with brief details of the field(s) you are working in.

Latest News

We are excited to announce that we will be running a workshop in 2019. It will be on the 2nd and 3rd April at the Crowne Plaza Hotel near Heathrow . 

The topics selected for the agenda this year include:

  • Bayesian approaches in pre-clinical
  • Brainstorming to prepare a paper on statistical approaches in Toxicology/Safety Assessment studies
  • Translation between pre-clinical and clinical
  • Exploration of new areas where we can have an impact (eg Data Sciences, Big Data, Machine Learning…)

All this, including overnight accommodation, dinner, breakfast and refreshments during the 2 days, is available for £205 per delegate.

Registration is open and spaces are limited.

To Register click here. 

Upcoming Events

The PSI Special Interest Group “Toxicology” have a series of regular FREE webinars dealing with statistical topics faced in toxicology and related fields. The presentations will run for an hour, with approximately 45 min presentation and a Q&A session in the remaining time. See section below for details of this years seminars.

Workshops

Since our inauguration in 2006 we have run a workshop approximately every 18 months. Our last workshop was run on the 24-25 April 2018 at the Crowne Plaza Hotel near Heathrow. The agenda focused on five topics: 

  • Self admin/abuse potential
  • Statistical methods for analysing the Ames-test
  • Role of the  Non-Clinical Statistician
  • Bio-Assay Validation
  • Statistics in Safety Testing
You can find all the slides under the PSI Resources page searching for: > Toxicology Sig > TOX SIG Workshop 2018 

 

Webinars

The PSI Special Interest Group “Toxicology” seminars for 2019 are as follows: 

Date

Title

Presenter

19 Feb 2019

Data Quality and Pre-Clinical Research

Professor Malcolm Macleod     

16 April 2019

ICH S1 revision and CAD process

TBC

18 June 2019

The Pig-a-Assay

Scientist(s) from Covance

17 Sept 2019

  

10 Dec 2019

  

To Register for a webinar please click on the link once it is available.

For all previous webinars click here.

 

Upcoming Events

A PSI ToxSIG webinar - Big Data, Data Science, AI and other buzzwords: What does the Data-Driven Hype mean for Pharmaceutical Analytics?

The last 15 years has seen a massive shift in the role of data and analytics, driven by the increased hype around big data, data science, machine learning and AI. This presents both challenges and opportunities for analytic teams. This webinar will strip back the hype to look at what these buzzwords really mean, and talk about the impact this is having on the role, remit and operating model of analytic teams in the life sciences industry.

PSI New Starters Half-Day Networking Event

An opportunity to meet statisticians from across the pharmaceutical industry in a relaxed and informal setting. An exciting program of events and a chance to work in small groups on a data analysis challenge. Lunch provided.

A PSI Training Course - Practical Approaches to Designing Adaptive Clinical Trials

This hands-on course will provide a deep dive into 4 software packages used to design adaptive clinical trials. The course will start by providing a general overview of adaptive designs, explaining the different type of adaptations possible and the benefits of each design. Following this, participants will be given the opportunity to have a go at designing trials in R (using RPACTS), EAST, FACTS, and nQuery.

PSI Training Course - Bayesian Practical Course using R and SAS

This practical training course will give a deep dive into performing Bayesian analyses in R and SAS. It is aimed at statisticians who need to be able to conduct Bayesian analyses as part of their day to day work. By the end of the course participants will be able to conduct their own analyses.

Medical Statistics Careers Event 2020

Our annual PSI Medical Statistics Careers Event, will be held at the De Montfort University in Leicester on Wednesday 4th March 2020.

A PSI Training Course - R for SAS Users

This course is aimed at Statisticians and Programmers experienced in SAS, but little or no experience with R. An Introduction to R studio and the R language, statistical graphics, programming statistical models, simulations and more…

Introduction To Industry Training Course 2020

The ITIT course will take 25 delegates new to the industry on a complete drug development experience from discovery to marketing. They will visit 6 companies from October 2020 to July 2021 to learn about 6 topics from experts in their field. The ITIT course will have 6 sessions in continental Europe and 3 - 4 sessions in the UK. It promises to be a truly memorable course.

Latest Jobs