Date: Tuesday 24th October 2023 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: PD Dr. Ulf Tölch (Berlin Institute of Health)
Who is this event intended for? Statisticians in Pharmaceutical Industry. What is the benefit of attending? Learning how to enhance efficient evidence generation of preclinical experiments.
Registration
Registration for this webinar is free to both Members of PSI and Non-Members.
Please click here to register.
Overview
PD Dr. Tölch will present a framework to foster efficient evidence generation in preclinical experiments and will illustrate the proposed approach using examples from various projects. This will be followed by Q&A.
Abstract The ultimate goal of preclinical research is to identify interventions that can be tested in clinical settings. Whereas safety and toxicity testing are highly regulated, efficacy testing is often variable consisting of several iterative experimental steps. Consequently, experimental design and statistical testing have to be adopted to the goals of each experiment. Additional factors like available resources, already collected evidence, and maturity of the project need to be considered as well. The ultimate goal is to efficiently identify effective interventions. Here, I present a framework to systematically adjust validity and reliability in preclinical experiments to foster efficient evidence generation. To illustrate this approach, I will present examples from our consultation project within the Berlin Institute of Health and on the national level for multicenter preclinical studies.
Speaker details
Speaker
Biography
PD Dr. Ulf Tölch
Ulf Tölch obtained his PhD in biology at LMU Munich. His research includes cognitive neuroscience, quantitative methods and statistical modelling of decision making. He currently serves as a research group leader at BIH QUEST Center for Responsible Research at Charité Universitätsmedizin. His research team explores robust methodological approaches in preclinical settings to inform and improve research decisions.
Scientific Meetings
PSI Pre-Clinical SIG Webinar: Adjusting Experimental & Statistical Approaches throughout Preclinical development pathways
Date: Tuesday 24th October 2023 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: PD Dr. Ulf Tölch (Berlin Institute of Health)
Who is this event intended for? Statisticians in Pharmaceutical Industry. What is the benefit of attending? Learning how to enhance efficient evidence generation of preclinical experiments.
Registration
Registration for this webinar is free to both Members of PSI and Non-Members.
Please click here to register.
Overview
PD Dr. Tölch will present a framework to foster efficient evidence generation in preclinical experiments and will illustrate the proposed approach using examples from various projects. This will be followed by Q&A.
Abstract The ultimate goal of preclinical research is to identify interventions that can be tested in clinical settings. Whereas safety and toxicity testing are highly regulated, efficacy testing is often variable consisting of several iterative experimental steps. Consequently, experimental design and statistical testing have to be adopted to the goals of each experiment. Additional factors like available resources, already collected evidence, and maturity of the project need to be considered as well. The ultimate goal is to efficiently identify effective interventions. Here, I present a framework to systematically adjust validity and reliability in preclinical experiments to foster efficient evidence generation. To illustrate this approach, I will present examples from our consultation project within the Berlin Institute of Health and on the national level for multicenter preclinical studies.
Speaker details
Speaker
Biography
PD Dr. Ulf Tölch
Ulf Tölch obtained his PhD in biology at LMU Munich. His research includes cognitive neuroscience, quantitative methods and statistical modelling of decision making. He currently serves as a research group leader at BIH QUEST Center for Responsible Research at Charité Universitätsmedizin. His research team explores robust methodological approaches in preclinical settings to inform and improve research decisions.
Training Courses
PSI Pre-Clinical SIG Webinar: Adjusting Experimental & Statistical Approaches throughout Preclinical development pathways
Date: Tuesday 24th October 2023 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: PD Dr. Ulf Tölch (Berlin Institute of Health)
Who is this event intended for? Statisticians in Pharmaceutical Industry. What is the benefit of attending? Learning how to enhance efficient evidence generation of preclinical experiments.
Registration
Registration for this webinar is free to both Members of PSI and Non-Members.
Please click here to register.
Overview
PD Dr. Tölch will present a framework to foster efficient evidence generation in preclinical experiments and will illustrate the proposed approach using examples from various projects. This will be followed by Q&A.
Abstract The ultimate goal of preclinical research is to identify interventions that can be tested in clinical settings. Whereas safety and toxicity testing are highly regulated, efficacy testing is often variable consisting of several iterative experimental steps. Consequently, experimental design and statistical testing have to be adopted to the goals of each experiment. Additional factors like available resources, already collected evidence, and maturity of the project need to be considered as well. The ultimate goal is to efficiently identify effective interventions. Here, I present a framework to systematically adjust validity and reliability in preclinical experiments to foster efficient evidence generation. To illustrate this approach, I will present examples from our consultation project within the Berlin Institute of Health and on the national level for multicenter preclinical studies.
Speaker details
Speaker
Biography
PD Dr. Ulf Tölch
Ulf Tölch obtained his PhD in biology at LMU Munich. His research includes cognitive neuroscience, quantitative methods and statistical modelling of decision making. He currently serves as a research group leader at BIH QUEST Center for Responsible Research at Charité Universitätsmedizin. His research team explores robust methodological approaches in preclinical settings to inform and improve research decisions.
Journal Club
PSI Pre-Clinical SIG Webinar: Adjusting Experimental & Statistical Approaches throughout Preclinical development pathways
Date: Tuesday 24th October 2023 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: PD Dr. Ulf Tölch (Berlin Institute of Health)
Who is this event intended for? Statisticians in Pharmaceutical Industry. What is the benefit of attending? Learning how to enhance efficient evidence generation of preclinical experiments.
Registration
Registration for this webinar is free to both Members of PSI and Non-Members.
Please click here to register.
Overview
PD Dr. Tölch will present a framework to foster efficient evidence generation in preclinical experiments and will illustrate the proposed approach using examples from various projects. This will be followed by Q&A.
Abstract The ultimate goal of preclinical research is to identify interventions that can be tested in clinical settings. Whereas safety and toxicity testing are highly regulated, efficacy testing is often variable consisting of several iterative experimental steps. Consequently, experimental design and statistical testing have to be adopted to the goals of each experiment. Additional factors like available resources, already collected evidence, and maturity of the project need to be considered as well. The ultimate goal is to efficiently identify effective interventions. Here, I present a framework to systematically adjust validity and reliability in preclinical experiments to foster efficient evidence generation. To illustrate this approach, I will present examples from our consultation project within the Berlin Institute of Health and on the national level for multicenter preclinical studies.
Speaker details
Speaker
Biography
PD Dr. Ulf Tölch
Ulf Tölch obtained his PhD in biology at LMU Munich. His research includes cognitive neuroscience, quantitative methods and statistical modelling of decision making. He currently serves as a research group leader at BIH QUEST Center for Responsible Research at Charité Universitätsmedizin. His research team explores robust methodological approaches in preclinical settings to inform and improve research decisions.
Webinars
PSI Pre-Clinical SIG Webinar: Adjusting Experimental & Statistical Approaches throughout Preclinical development pathways
Date: Tuesday 24th October 2023 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: PD Dr. Ulf Tölch (Berlin Institute of Health)
Who is this event intended for? Statisticians in Pharmaceutical Industry. What is the benefit of attending? Learning how to enhance efficient evidence generation of preclinical experiments.
Registration
Registration for this webinar is free to both Members of PSI and Non-Members.
Please click here to register.
Overview
PD Dr. Tölch will present a framework to foster efficient evidence generation in preclinical experiments and will illustrate the proposed approach using examples from various projects. This will be followed by Q&A.
Abstract The ultimate goal of preclinical research is to identify interventions that can be tested in clinical settings. Whereas safety and toxicity testing are highly regulated, efficacy testing is often variable consisting of several iterative experimental steps. Consequently, experimental design and statistical testing have to be adopted to the goals of each experiment. Additional factors like available resources, already collected evidence, and maturity of the project need to be considered as well. The ultimate goal is to efficiently identify effective interventions. Here, I present a framework to systematically adjust validity and reliability in preclinical experiments to foster efficient evidence generation. To illustrate this approach, I will present examples from our consultation project within the Berlin Institute of Health and on the national level for multicenter preclinical studies.
Speaker details
Speaker
Biography
PD Dr. Ulf Tölch
Ulf Tölch obtained his PhD in biology at LMU Munich. His research includes cognitive neuroscience, quantitative methods and statistical modelling of decision making. He currently serves as a research group leader at BIH QUEST Center for Responsible Research at Charité Universitätsmedizin. His research team explores robust methodological approaches in preclinical settings to inform and improve research decisions.
Careers Meetings
PSI Pre-Clinical SIG Webinar: Adjusting Experimental & Statistical Approaches throughout Preclinical development pathways
Date: Tuesday 24th October 2023 Time: 14:00-15:00 BST | 15:00-16:00 CEST Speaker: PD Dr. Ulf Tölch (Berlin Institute of Health)
Who is this event intended for? Statisticians in Pharmaceutical Industry. What is the benefit of attending? Learning how to enhance efficient evidence generation of preclinical experiments.
Registration
Registration for this webinar is free to both Members of PSI and Non-Members.
Please click here to register.
Overview
PD Dr. Tölch will present a framework to foster efficient evidence generation in preclinical experiments and will illustrate the proposed approach using examples from various projects. This will be followed by Q&A.
Abstract The ultimate goal of preclinical research is to identify interventions that can be tested in clinical settings. Whereas safety and toxicity testing are highly regulated, efficacy testing is often variable consisting of several iterative experimental steps. Consequently, experimental design and statistical testing have to be adopted to the goals of each experiment. Additional factors like available resources, already collected evidence, and maturity of the project need to be considered as well. The ultimate goal is to efficiently identify effective interventions. Here, I present a framework to systematically adjust validity and reliability in preclinical experiments to foster efficient evidence generation. To illustrate this approach, I will present examples from our consultation project within the Berlin Institute of Health and on the national level for multicenter preclinical studies.
Speaker details
Speaker
Biography
PD Dr. Ulf Tölch
Ulf Tölch obtained his PhD in biology at LMU Munich. His research includes cognitive neuroscience, quantitative methods and statistical modelling of decision making. He currently serves as a research group leader at BIH QUEST Center for Responsible Research at Charité Universitätsmedizin. His research team explores robust methodological approaches in preclinical settings to inform and improve research decisions.
Upcoming Events
PSI Introduction to Industry Training (ITIT) Course - 2025/2026
An introductory course giving an overview of the pharmaceutical industry and the drug development process as a whole, aimed at those with 1-3 years' experience. It comprises of six 2-day sessions covering a range of topics including Research and Development, Toxicology, Data Management and the Role of a CRO, Clinical Trials, Reimbursement, and Marketing.
Joint PSI/EFSPI Visualisation SIG 'Wonderful Wednesday' Webinars
Our monthly webinar explores examples of innovative data visualisations relevant to our day to day work. Each month a new dataset is provided from a clinical trial or other relevant example, and participants are invited to submit a graphic that communicates interesting and relevant characteristics of the data.
PSI Book Club Webinar: Atomic Habits - The Science of Getting Your Act Together
The book club’s usual focus is to read and discuss professional development books. In this short format event you can more easily develop you career without the commitment of reading the whole book - simply listen to the 1-hour long podcast before joining the interactive session on 21 May.
PSI Webinar: Methods and tools integrating clinical trial evidence with historical or real-world data, Bayesian borrowing, and causal inference
This webinar is organised by the RWD SIG and the Historical Data SIG. We will review recent methods, applications, and tools of integrating subject-level-data from clinical trial with external data using Bayesian methods and/or causal inference methods.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
PSI Webinar: Applying the Estimand Framework to Clinical Pharmacology Trials with a Case Study in Bioequivalance
This will be a 45 minute webinar which will explain the topic presented in the published paper, ‘Applying the Estimand Framework to Clinical Pharmacology Trials with a Case Study in Bioequivalance’. There will be 15 minutes for a panel Q&A with some of the authors following the presentation.
PSI Webinar: Methodology and first results of the iRISE (improving Reproducibility In SciencE) consortium
This 1-hour webinar will be an opportunity to hear about the methodology and first results of the iRISE consortium. iRISE is working towards a better understanding of reproducibility and the interventions that work to improve it. At the end of the presentation there will also be the opportunity to ask questions.
One-day PSI/PHUSE Event: Change Management for Moving to R/Open-Source
This one-day event focuses on the comprehensive management of transitioning to R/Open-Source, addressing the challenges and providing actionable insights. Attendees will participate in sessions covering essential topics such as training best practices, creating strategic plans, making the case to senior management, and managing both statistical and programming aspects of the transition.
PSI Book Club - The Art of Explanation: How to Communicate with Clarity and Confidence
Develop your non-technical skills by reading The Art of Explanation by Ros Atkins and joining the Sept-Dec 2025 book club. You will be invited to join facilitated discussions of the concepts and ideas and apply skills from the book in-between sessions.
This course is aimed at biostatisticians with no or some pediatric drug development experience who are interested to further their understanding. We will give you an introduction to the pediatric drug development landscape. This will include identifying the key regulations and processes governing pediatric development, a discussion on the needs and challenges when conducting pediatric research and a focus on the ways to overcome these challenges from a statistical perspective.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
The program will feature insightful sessions led by distinguished invited speakers, alongside a poster session showcasing the latest advancements in the field. Further details will be provided.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
This is an exciting, new opportunity for an experienced Statistician looking to take the next step in their career. Offered as a remote or hybrid position aligned with our site in Harrogate, North Yorkshire.