To be presented byCarl-Fredrik Burman & Lisa Hampson
Regulatory agencies require strong control of the Type I Error for all confirmatory statistical tests. Multiplicity issues can arise for several reasons, e.g.: the possibility of winning on two different endpoints (like PFS and OS), interim analyses, or testing for effects in several patient groups. This course will focus on the principles underlying multiple comparison procedures and their applications to confirmatory clinical trials. We will describe simple ways to construct valid multiple tests, and will explore how tests can be incorporated into recycling strategies. Group-sequential and some common adaptive tests will also be described. Concepts will be introduced through a combination of lectures, exercises, and discussion sessions where groups will focus on the issues that might be encountered when designing and communicating statistical tests.
The following topics will be covered:
Introduction to Multiple Testing
Recycling and graphical methods
Group sequential and adaptive designs
Operating characteristics and improving them using correlations
Using decision analysis to optimise multiple testing procedures
Registration
Early bird (up to & including 9th April)
After 9th April
PSI Member
£295 + VAT
£345 + VAT
Non-Member
£390 + VAT
£440 + VAT
Registration is now closed.
Registration costs include lunch and refreshments. PSI are holding a limited number of hotel rooms on 8th May which will be allocated on a first come first served basis. Please contact psi@mci-group.com to reserve a room. Rooms are charged at £109.00 per room including breakfast.
Scientific Meetings
PSI Training Course: Multiple Testing in Confirmatory Clinical Trials
To be presented byCarl-Fredrik Burman & Lisa Hampson
Regulatory agencies require strong control of the Type I Error for all confirmatory statistical tests. Multiplicity issues can arise for several reasons, e.g.: the possibility of winning on two different endpoints (like PFS and OS), interim analyses, or testing for effects in several patient groups. This course will focus on the principles underlying multiple comparison procedures and their applications to confirmatory clinical trials. We will describe simple ways to construct valid multiple tests, and will explore how tests can be incorporated into recycling strategies. Group-sequential and some common adaptive tests will also be described. Concepts will be introduced through a combination of lectures, exercises, and discussion sessions where groups will focus on the issues that might be encountered when designing and communicating statistical tests.
The following topics will be covered:
Introduction to Multiple Testing
Recycling and graphical methods
Group sequential and adaptive designs
Operating characteristics and improving them using correlations
Using decision analysis to optimise multiple testing procedures
Registration
Early bird (up to & including 9th April)
After 9th April
PSI Member
£295 + VAT
£345 + VAT
Non-Member
£390 + VAT
£440 + VAT
Registration is now closed.
Registration costs include lunch and refreshments. PSI are holding a limited number of hotel rooms on 8th May which will be allocated on a first come first served basis. Please contact psi@mci-group.com to reserve a room. Rooms are charged at £109.00 per room including breakfast.
Training Courses
PSI Training Course: Multiple Testing in Confirmatory Clinical Trials
To be presented byCarl-Fredrik Burman & Lisa Hampson
Regulatory agencies require strong control of the Type I Error for all confirmatory statistical tests. Multiplicity issues can arise for several reasons, e.g.: the possibility of winning on two different endpoints (like PFS and OS), interim analyses, or testing for effects in several patient groups. This course will focus on the principles underlying multiple comparison procedures and their applications to confirmatory clinical trials. We will describe simple ways to construct valid multiple tests, and will explore how tests can be incorporated into recycling strategies. Group-sequential and some common adaptive tests will also be described. Concepts will be introduced through a combination of lectures, exercises, and discussion sessions where groups will focus on the issues that might be encountered when designing and communicating statistical tests.
The following topics will be covered:
Introduction to Multiple Testing
Recycling and graphical methods
Group sequential and adaptive designs
Operating characteristics and improving them using correlations
Using decision analysis to optimise multiple testing procedures
Registration
Early bird (up to & including 9th April)
After 9th April
PSI Member
£295 + VAT
£345 + VAT
Non-Member
£390 + VAT
£440 + VAT
Registration is now closed.
Registration costs include lunch and refreshments. PSI are holding a limited number of hotel rooms on 8th May which will be allocated on a first come first served basis. Please contact psi@mci-group.com to reserve a room. Rooms are charged at £109.00 per room including breakfast.
Journal Club
PSI Training Course: Multiple Testing in Confirmatory Clinical Trials
To be presented byCarl-Fredrik Burman & Lisa Hampson
Regulatory agencies require strong control of the Type I Error for all confirmatory statistical tests. Multiplicity issues can arise for several reasons, e.g.: the possibility of winning on two different endpoints (like PFS and OS), interim analyses, or testing for effects in several patient groups. This course will focus on the principles underlying multiple comparison procedures and their applications to confirmatory clinical trials. We will describe simple ways to construct valid multiple tests, and will explore how tests can be incorporated into recycling strategies. Group-sequential and some common adaptive tests will also be described. Concepts will be introduced through a combination of lectures, exercises, and discussion sessions where groups will focus on the issues that might be encountered when designing and communicating statistical tests.
The following topics will be covered:
Introduction to Multiple Testing
Recycling and graphical methods
Group sequential and adaptive designs
Operating characteristics and improving them using correlations
Using decision analysis to optimise multiple testing procedures
Registration
Early bird (up to & including 9th April)
After 9th April
PSI Member
£295 + VAT
£345 + VAT
Non-Member
£390 + VAT
£440 + VAT
Registration is now closed.
Registration costs include lunch and refreshments. PSI are holding a limited number of hotel rooms on 8th May which will be allocated on a first come first served basis. Please contact psi@mci-group.com to reserve a room. Rooms are charged at £109.00 per room including breakfast.
Webinars
PSI Training Course: Multiple Testing in Confirmatory Clinical Trials
To be presented byCarl-Fredrik Burman & Lisa Hampson
Regulatory agencies require strong control of the Type I Error for all confirmatory statistical tests. Multiplicity issues can arise for several reasons, e.g.: the possibility of winning on two different endpoints (like PFS and OS), interim analyses, or testing for effects in several patient groups. This course will focus on the principles underlying multiple comparison procedures and their applications to confirmatory clinical trials. We will describe simple ways to construct valid multiple tests, and will explore how tests can be incorporated into recycling strategies. Group-sequential and some common adaptive tests will also be described. Concepts will be introduced through a combination of lectures, exercises, and discussion sessions where groups will focus on the issues that might be encountered when designing and communicating statistical tests.
The following topics will be covered:
Introduction to Multiple Testing
Recycling and graphical methods
Group sequential and adaptive designs
Operating characteristics and improving them using correlations
Using decision analysis to optimise multiple testing procedures
Registration
Early bird (up to & including 9th April)
After 9th April
PSI Member
£295 + VAT
£345 + VAT
Non-Member
£390 + VAT
£440 + VAT
Registration is now closed.
Registration costs include lunch and refreshments. PSI are holding a limited number of hotel rooms on 8th May which will be allocated on a first come first served basis. Please contact psi@mci-group.com to reserve a room. Rooms are charged at £109.00 per room including breakfast.
Careers Meetings
PSI Training Course: Multiple Testing in Confirmatory Clinical Trials
To be presented byCarl-Fredrik Burman & Lisa Hampson
Regulatory agencies require strong control of the Type I Error for all confirmatory statistical tests. Multiplicity issues can arise for several reasons, e.g.: the possibility of winning on two different endpoints (like PFS and OS), interim analyses, or testing for effects in several patient groups. This course will focus on the principles underlying multiple comparison procedures and their applications to confirmatory clinical trials. We will describe simple ways to construct valid multiple tests, and will explore how tests can be incorporated into recycling strategies. Group-sequential and some common adaptive tests will also be described. Concepts will be introduced through a combination of lectures, exercises, and discussion sessions where groups will focus on the issues that might be encountered when designing and communicating statistical tests.
The following topics will be covered:
Introduction to Multiple Testing
Recycling and graphical methods
Group sequential and adaptive designs
Operating characteristics and improving them using correlations
Using decision analysis to optimise multiple testing procedures
Registration
Early bird (up to & including 9th April)
After 9th April
PSI Member
£295 + VAT
£345 + VAT
Non-Member
£390 + VAT
£440 + VAT
Registration is now closed.
Registration costs include lunch and refreshments. PSI are holding a limited number of hotel rooms on 8th May which will be allocated on a first come first served basis. Please contact psi@mci-group.com to reserve a room. Rooms are charged at £109.00 per room including breakfast.
Upcoming Events
Joint PSI/EFSPI Visualisation SIG 'Wonderful Wednesday' Webinars
Our monthly webinar explores examples of innovative data visualisations relevant to our day to day work. Each month a new dataset is provided from a clinical trial or other relevant example, and participants are invited to submit a graphic that communicates interesting and relevant characteristics of the data.
The event will open with an overview on drug development in women’s health from a clinician perspective. This talk is followed by talks about statistical challenges when planning IVF studies and analysing the menstrual cycles.
This webinar will provide an overview of surrogacy for licensing and reimbursement. In turn, the need of extensions of the SPIRIT and CONSORT statement will be defined and outlined, with case studies to support.
Joint PSI/EFSPI Pre-Clinical SIG Webinar: Virtual Control Groups in Toxicity Studies
Lea Vaas will present how replacement of concurrent control animals by Virtual Control Groups (VCGs) in systemic toxicity studies may help in contributing to the 3R's principle of animal experimentation: Reduce, Refine, Replace.
Joint PSI/EFSPI Data Science SIG Webinar: Developing Digital Measures (Digital Biomarkers) in Drug Development – insights from Mobilise D consortium
We will share a brief overview of what Mobilise D is and why it is an important step stone in the development of digital biomarkers, and how Mobilise D outputs can be relevant for you.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
PSI Webinar: Development of Gene Therapies: Strategic, Scientific, Regulatory and Access Considerations
This webinar will cover the history of cell/gene therapy, major regulatory advances, the role of quantitative scientists in drug development of these novel therapeutics, and discuss opportunities for innovation and product advancement.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
PSI Introduction to Industry Training (ITIT) Course - 2024/2025
An introductory course giving an overview of the pharmaceutical industry and the drug development process as a whole, aimed at those with 1-3 years' experience. It comprises of six 2-day sessions covering a range of topics including Research and Development, Toxicology, Data Management and the Role of a CRO, Clinical Trials, Reimbursement, and Marketing.
This networking event is aimed at statisticians that are new to the pharmaceutical industry who wish to meet colleagues from different companies and backgrounds.
Statisticians in the Pharmaceutical Industry Executive Office: c/o MCI UK Ltd | Unit 24/22 South | Building 4000 | Langstone Park| Langstone Road | Havant | PO9 1SA | UK