Video-on-Demand Library

07 December 2023

Arthur Allignol, Antonio Remiro-Azócar,  Robert Hemmings, and Nicholas Latimer.

Over the past years, areas of clinical development and patient access / health technology assessment (HTA) have moved closer together. However, both areas differ in how they approach their respective research or policy questions. While the estimand framework is being the focus in clinical development, HTA is being viewed through the lens of the PICO framework. This might lead to mutual misunderstandings and ultimately prevent timely patient access due to evidence gaps. Additionally, the Target Trial Emulation framework has become popular in the Real-World Data setting, and shares some commonalities with the estimand and PICO frameworks. This webinar brought together renowned experts in their respective fields, who provided an introduction to these three concepts, illustrated with examples, and discussed their commonalities and differences.

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