Core Committee (L-R): Fetene Tekle (Janssen), Gareth Thomas (former member and chair), Bernd Igl (Boehringer Ingelheim), Eloisa Brook (chair, GlaxoSmithKline), Jim Saul (Covance) and Phillip Jarvis (former member, Novartis). Luc Essermeant (Sanofi) and Ezgi Tanriver-Ayder (GlaxoSmithKline) have also joined the team.
To provide a forum to discuss and advance statistical topics related to Research, Discovery (including efficacy models), Regulatory and Investigative Toxicology/Safety Assessment and to promote the involvement of Statisticians in these areas.
Our membership consists of statisticians at CROs, pharmaceutical companies and academia who are working in preclinical (animal and cell based experiments) areas such as:
- Discovery
- Good statistical practice in in-vitro, ex-vivo and in-vivo assay development
- Reproducibility and Translation from pre-clinical to clinical
- Toxicogenomics
- Genetic Toxicology
- Acute Toxicology
- General Toxicology
- Eco-Toxicology
- Toxicokinetics
- DMPK / Pharmacokinetics
- ECG
- Immuno Toxicology
- Histopathology
- Pharmacology
- Developmental and Reproductive Toxicology
- Carcinogenicity
We discuss diverse topics ranging from Dog Telemetry data analysis to Decision Trees, from Bayesian methods to dealing with irate study directors, and now have a list of over 50 affiliates on our e-mail distribution list.
Find out more in our video overview:
The PSI Pre-clinical Special Interest Group have a series of regular FREE webinars dealing with statistical topics faced in pre-clinical and related fields. The presentations will run for an hour, with approximately 45 min presentation and a Q&A session in the remaining time. See section below for details of this year’s webinars. Please note that these events take place online via Zoom, and has a limited number of places available.
The PSI Pre-Clinical Special Interest Group seminars for 2023 are as follows:
Date | Title | Presenter | |
14 March 2023 | End-user Tool for Immunogenicity Cut-points Calculation | Dr. Els Pattyn, Ablynx | To access the video on demand, please click here |
27 June 2023 | EC50 Estimation based on Multi-Donor Dose-Response Data | Dr. Weiliang Qiu and Dr. Cheng Wenren, Sanofi | For more information and to register, please click here |
| 24 October 2023 | Adjusting Experimental and Statistical Approaches throughout Preclinical Development Pathways | PD Dr. Ulf Tölch, Berlin Institute of Health at Charité | TBA |
Please email us with any questions or comments and if you would like to join our mailing list.
