One Day Course: Practicalities in designing, grant funding, setting up and running a Continual Reassessment Method (CRM) dose finding phase I trial

  • Dates: 28 – 28 Nov, 2018
  • How to find us: Seminar room 6.075, Level 6 Worsley Building, University of Leeds, Leeds, LS2 9NL

Course Tutors

This course is delivered by a group of statisticians and trial managers with a wealth of expertise in running CRM trials. The group was formed through the NIHR early phase clinical trials statistics group and consists of:

Andrew Hall, Debbie Sherratt and Sam Hinsley: Clinical Trials Research Unit, University of Leeds

Christina Yap and Eszter Nagy: Cancer Research UK Clinical Trials Unit, University of Birmingham

Graham Wheeler: Cancer Research UK & UCL Cancer Trials Centre, University College London

Jane Holmes: Oxford Clinical Trials Research Unit, University of Oxford

Sharon Love: MRC Clinical Trials Unit, University College London

Target Audience

This course is designed for anyone running a phase I dose finding trial who wants to learn more about the CRM. The course focuses on the CRM concept and practicalities, rather than the pure associated statistical methodology, and is aimed at clinicians, data managers, trial managers and statisticians, in both academic and pharmaceutical institutions.

Cost and Registration

Academic employees - £150

Industry/commercial employees - £300

Last registration date - 16th November

Registration and further information can be found at:

Questions and queries may be directed by email to Andrew Hall or Sam Hinsley (

Please click here to view the flyer.

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