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DTSTART:20231002T030000
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BEGIN:VEVENT
DESCRIPTION:Time: \;14:00- 15:00 UK time\n\nAcross a range of scientifi
c disciplines\, concerns have been raised about the reproducibility of res
earch findings. This has generally been considered to be a bad thing. \nCe
rtainly\, some of the failure to replicate key findings is due to poor exp
erimental design\, underpowered experiments and poor reporting of neutral
or negative studies or inconvenient outcomes. To the extent that these pro
blems might be addresses\, they represent an opportunity for improvement\,
an opportunity to reduce research waste.\nHowever\, in other situations i
t appears that the failure to replicate may have been due to the influence
of some latent nuisance variable\, present in one lab but not another\, w
hich had a biological effect on the phenomenon being tested. Understanding
better the nature of these variables\, and how their influence is made ma
nifest\, provides opportunities for deeper biological understanding. \nMal
colm Macleod will discuss issues of research waste\; of replication\; and
of how these issues might be harnessed to improve research.\nBiography\nMa
lcolm Macleod is a clinician scientist and neurologist who is concerned wi
th how we might increase the value of biomedical research\, both through i
mproving the quality of primary research and through better exploitation o
f what is already known.\n\n\nRegistration\nThis webinar is free to attend
. \n\nRegistration is now closed. \;\n
DTEND:20190219T140000Z
DTSTAMP:20240329T020458Z
DTSTART:20190219T130000Z
LOCATION:
SEQUENCE:0
SUMMARY:PSI Toxicology SIG Webinar - Data Quality and Reproducibility in Pr
eclinical Research
UID:RFCALITEM638472746986410622
X-ALT-DESC;FMTTYPE=text/html:Time: \;14:00- 15:00 UK t
ime
\n
\n
Across a range of scientific disciplines\, concerns have been raised about the reproducibility of research findings. This has generally been considered to be a bad thing.
\nCertainly\, some of the failure to replicate key findings is due to poor experimental design\, underpowered experiments and poor reporting of neutral or negative studie s or inconvenient outcomes. To the extent that these problems might be add resses\, they represent an opportunity for improvement\, an opportunity to reduce research waste.
\nHowever\, in other situations it appears t hat the failure to replicate may have been due to the influence of some la tent nuisance variable\, present in one lab but not another\, which had a biological effect on the phenomenon being tested. Understanding better the nature of these variables\, and how their influence is made manifest\, pr ovides opportunities for deeper biological understanding.
\nMalcolm Ma cleod will discuss issues of research waste\; of replication\; and of how these issues might be harnessed to improve research.Malcolm Macleod is a clinician scientist and neurologist who is c
oncerned with how we might increase the value of biomedical research\, bot
h through improving the quality of primary research and through better exp
loitation of what is already known.
\n
\n
This webinar is free to attend.
\n
\nRegistration is n
ow closed. \;