17PSILON PSI web banner
This course will take place on Sunday 14th May from 14:00. You can register your place through the conference registration system.

Cytel Pre-Conference Course

Sample Size, Power, and Adaptive Trial Design for Late Stage Studies: A Practical Hands-on Workshop

​​The purpose of our workshop at PSI 2017 is to first better familiarize attendees with the underlying statistical methods, then instruct you on designing related trials of greatest interest to you and your organization. Case studies of actual adaptive trials will both illustrate the use of the methodologies and serve as hands-on design examples.

Over the course of 25 years, East® has become an industry standard platform for planning and monitoring early and later stage clinical trials. You do not have to be an East user to benefit from the workshop, but the trial design examples will use the software (provided to all who bring a PC laptop).

Part One
We begin with a trial design and software capabilities overview including:
- Sample size and power calculations
- Adjustments for multiple comparisons
- Early stopping for efficacy/futility
- Sample size re-estimation
- Adaptive dose selection
- Survival endpoints
- Enrollment/event forecasting

Part Two
In the workshop's second part attendees can work through hands-on exercises using the software.

Prepared examples covering many of the stated topics will be provided, with attendees choosing which to work on. Our instruction team will coach attendees throughout the design process, including running simulations to predict likely outcomes.

​2017 Workshop Instructors: Pantellis Vlachos and Yannis Jemiai

​Additional Benefits
​All registrants will receive the complete and latest version of East® to use for 30 days following the workshop.

Refreshments will be provided gratis.

Latest News

Show all news

EventsFuture Events

  • Patient Engagement in Clinical Trials Webinar - Dates: 13 – 13 Jun, 2017

    Following on from the successful and thought-provoking presentation at last year’s PSI conference by Paul Wicks from PatientsLikeMe, this webinar will continue to explore the ways in which patients are influencing the design of new clinical trials.
  • BBS / PSI One-day Event on Cancer Immunotherapy - Dates: 15 Jun, 2017

    This joint Basel Biometric Society / PSI one day meeting will present an overview of the science and potential statistical challenges across a range of topics covering early and late phases of development, regulatory and health technology assessments.
Merck Logo2

Associate Director, Biostatistician



Medical Statistician / Senior Medical Statistician



Associate Director, Statistics Team leader - Early Clinical Development



Early Clinical Development – various levels



Biostatistics Head of Department



Principal Statistician – Centralised Statistical Monitoring



Clinical Trial Design Methodology Expert - Statistical Innovation Team